FIELD: medicine; pharmacology.
SUBSTANCE: revealed are systems and sets for delivery of medical products, liberating anaesthetic of short-term action, such as bupivacaine. Method of introduction and preparation of such systems are also revealed. Systems of medical products delivery include quickly operating geleous carrier and an anaesthetic dissolved or dispersed in a geleous medium. The geleous medium contains bioerosive, biologically compatible polymer with average molecular mass of 3,000 to 10,000 and a dissolvent not admixed with water in quantity effective for plasticisation of polymer and formation of gel with polymer. One of the method for measuring the effectiveness of medical products delivery system is the effectiveness ratio which can be regulated, for example, by the composition of geleous medium , to achieve a desirable profile of liberation.
EFFECT: effective anaesthesia due to liberation of the predetermined quantity of anaesthetic of short-term action in operated area during a long period of time.
34 cl, 14 ex, 15 dwg
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Authors
Dates
2008-09-10—Published
2003-10-31—Filed