COMPOSITION WITH DELAYED RELEASE, INCLUDING OCTREOTIDE AND TWO OR MORE POLYLACTIDE AND GLYCOLIDE COPOLYMERS Russian patent published in 2012 - IPC A61K9/16 A61K38/31 A61P35/00

Abstract RU 2464972 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to medicine and deals with composition with delayed release, which includes as active ingredient octreotide or its pharmaceutically acceptable salt and two or more different copolymers of polylactide and glycolide (PLGA), and said PLGA are present in form of mixture of polymers and at least two PLGAs are linear.

EFFECT: invention ensures considerable reduction of level of active ingredient fluctuation in plasma.

16 cl, 5 ex, 4 tbl

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RU 2 464 972 C2

Authors

Petersen Khol'Ger

Al'Khajm Markus

Dates

2012-10-27—Published

2006-12-20—Filed