METHOD FOR OBTAINING 1R,2S-METOXAMINE, THERAPEUTIC APPLICATION THEREOF (VERSIONS) AND PHARMACEUTICAL COMPOSITION Russian patent published in 2008 - IPC A61K31/137 A61P11/02 A61P9/02 A61P1/00 A61P27/08 

Abstract RU 2332989 C2

FIELD: medicine; pharmacology.

SUBSTANCE: invention describes pharmaceutical compositions for treatment of indications when the alpha adrenoreceptor agonist is used containing its physiologically acceptable salt, admixed or bound with pharmaceutically acceptable medium. Also, the method for obtaning 1R,2S-metoxamine is described. Isomer of 1R,2S-metoxamine possesses hyperactivity as an alpha agonist in comparison with known racemate of metoxamine. It can be used locally for effective treatment of incontience of feces in low doses without local or systematic by-effects, for example, without influence on blood pressure. 1R, 2S-metoxamine can be used in low doses and without essential by-effects for treatment of other disorders and disturbances of gastroenteric tract.

EFFECT: increased efficiency of the composition and the method for treatment.

71 cl, 6 tbl, 11 dwg, 4 ex

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RU 2 332 989 C2

Authors

Barras Norman

Tompson Dzhefri Martin

Dates

2008-09-10Published

2002-12-20Filed