METHOD OF IBUPROFEN QUANTITATION Russian patent published in 2008 - IPC G01N33/15 A61K31/192 

FIELD: medicine.

SUBSTANCE: invention refers to medicine and can be used in analytical laboratories for standardisation and quality assurance of medical products. The method involves preparing solutions of defined substance and the standard reference solution. The 0.1 M sodium hydroxide solution is used as a dissolvent for preparation of a defined solution, potassium ferricyanide being used as the standard reference solution. The method further includes measuring optical density of a defined solution and reference potassium ferricyanide solution using spectrophotometer with the 259 nm wavelength; calculating results from the formula; entering recalculation factor therein.

EFFECT: increased reproducibility of results of definition, sensitivity of the analysis; reduced labour input, analysis error; ruling out the use of toxic reactants; unifying analysis techniques.

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