REMEDY POTENTIATING ANTI-TUMOUR EFFECT, AND ANTI-TUMOUR REMEDY Russian patent published in 2008 - IPC A61K31/513 A61K31/4412 A61K31/53 A61K47/22 A61P35/00 

Abstract RU 2334517 C2

FIELD: medicine.

SUBSTANCE: anti-tumour remedy includes, as active ingredients, tegafur in therapeutically efficient amount, gimeracil in amount efficient for enhancing anti-tumour effect, potassium oteracil in amount efficient for inhibiting side-effect, and at least one element selected from the group consisting of pholinic acid and its pharmacologically acceptable salts in amount efficient for enhancing anti-tumour effect. Molar ratio of tegafur: gimeracil: potassium oteracil: at least one element selected from group consisting of folinic acid and its pharmacologically acceptable salts is 1:0.4:1: 0.01 to 10. Application of combined medication tegafur/gimeracil/potassium oteracil in combination with potassium folinate essentially increases anti-tumour activity without aggravating toxicity.

EFFECT: enhanced anti-tumour effect.

13 cl, 3 tbl, 3 ex

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RU 2 334 517 C2

Authors

Utida Dzundzi

Sudo Kojo

Dates

2008-09-27Published

2004-03-11Filed