FIELD: medicine.
SUBSTANCE: anti-tumour remedy includes, as active ingredients, tegafur in therapeutically efficient amount, gimeracil in amount efficient for enhancing anti-tumour effect, potassium oteracil in amount efficient for inhibiting side-effect, and at least one element selected from the group consisting of pholinic acid and its pharmacologically acceptable salts in amount efficient for enhancing anti-tumour effect. Molar ratio of tegafur: gimeracil: potassium oteracil: at least one element selected from group consisting of folinic acid and its pharmacologically acceptable salts is 1:0.4:1: 0.01 to 10. Application of combined medication tegafur/gimeracil/potassium oteracil in combination with potassium folinate essentially increases anti-tumour activity without aggravating toxicity.
EFFECT: enhanced anti-tumour effect.
13 cl, 3 tbl, 3 ex
Authors
Dates
2008-09-27—Published
2004-03-11—Filed