APPLICATION OF COMPOUNDINGS, EFFECTIVE AS SELECTIVE OPIATE RECEPTOR MODULATORS Russian patent published in 2008 - IPC A61K31/402 A61P1/00 A61P3/04 A61P1/06 

Abstract RU 2336871 C2

FIELD: medicine.

SUBSTANCE: application of asimadolin or its pharmaceutically acceptable sals is proposed for preparation of pharmaceuticals for indigestion treatment: gastroparesis, gastroatonia, gastroparalysis and the digestive tract stenosis in particular. Medication is effective for tonus modulating of the digestive tract, satiation. Registered, that asimadolin (N-methyl-N-[(1S)-1-phenil-2-((3S)-3-hydroxipyrrolidin-1-il)ethyl]-2,2-dyphenylacetylene (EMD 61753), a selective modulator of the opiate kappa-receptors) depending on the dose, contributes to consumed food volume increase without afterdinner symptoms: bloat, nausea, pain after meal.

EFFECT: creation for effective medication for tonus modulating of digestive tract, satiation.

8 cl, 5 dwg, 4 tbl

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RU 2 336 871 C2

Authors

Veber Frank

Jakob Jutta

Barber Ehndr'Ju

Gottshlikh Rudol'F

Dates

2008-10-27Published

2003-04-28Filed