APPLICATION OF N-DISMETILKLOSAPINE FOR HUMAN NEUROPSYCHIATRIC DISEASES TREATMENT Russian patent published in 2008 - IPC A61K31/5513 A61P25/18 

FIELD: medicine.

SUBSTANCE: application of N-dismetilklosapine is proposed for production of a medicine, increasing the muscarine receptor activity level, for facilitation of condition or treatment of schizofrenia. N-dismetil - klosapine is klosapine metabolite, applied for schizophrenia treatment. It is stated, that N-dismetilklosapine differs from klosapine with prepotent activation of muscarine receptors, including influence on M₃- and M₅- muscarine receptors (klosapin does not affect the latter), the capability of penetration into the central nervous system through the hematoencephalic barrier.

EFFECT: creation of medication, increasing muscarine receptor activity level, for facilitation of condition or treatment of schizophrenia.

10 cl, 3 dwg, 2 tbl