FIELD: chemistry, pharmacology.
SUBSTANCE: present invention relates to particular method for diastereoselective synthesis of racemic diorganosilyl-bis-(2-methylbenzo-[e]indenyl)zirconium compounds of formula (I): by interreaction of silyl bridged bis-indenyl ligand bonded with dihalogenylzirconium-bis(3,5-di-tert-butylphenoxide), and base, resulting in diorganosilyl-bis-(2-methylbenzo-[e]indenyl)zirconium bis(3,5-di-tert-butylphenoxide) formation, followed by phenoxy-groups to X groups change using appropriate substitution agents, and eventually obtaining compounds of formula (I); where substitutes X may be same or different and indicate halogen atom, and substitutes R may be same or different and indicate lower alkyl.
EFFECT: improvement of technique.
15 cl, 7 ex
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Authors
Dates
2008-10-27—Published
2003-10-22—Filed