FIELD: medicine; dermatovenerology.
SUBSTANCE: daily before each injection of benzylpenicillin sodium salt a patient gets intravenously within 15 minutes osmotic diuretic mannitol in the dosage 2 g/kg of patient's body weight. In 30 minutes after its completion they administer intravenously 12 million units of benzylpenicillin sodium salt, the course of treatment is 10 days. At this penetration of benzylpenicillin to the arachnoid cavity increases in the conditions of temporary osmotic burst of the hematoencephalic barrier by means of mannitol effect, also sanitation of the nervous system is provided.
EFFECT: method allows to increase efficiency of the specific therapy of advanced neurosyphilis; to minimise side effects; is easy in production and is widely available in hospitals.
4 tbl, 2 ex
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