METHOD OF ENANTIOSELECTIVE HYDRATION OF AMINOALCOHOLS Russian patent published in 2008 - IPC C07C213/00 C07C215/34 C07D333/20 

Abstract RU 2340594 C2

FIELD: chemistry.

SUBSTANCE: method of enantiomeric obtaining aminoalcohols of formula I in which R1, R2 and n have values given in invention formula, lies in enantioselective hydration of aminoketones in presence of non-racemic catalyst, representing complex of transitive metal, which contains one or more metals and its salts, selected from group, including rhodium, iridium, ruthenium and palladium, in which transitive metal forms complex with chiral diphosphine ligand A.

EFFECT: improvement of synthesis of aminoalcohols, which are acceptable as precursors for obtaining anti-depressants.

11 cl, 6 ex

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RU 2 340 594 C2

Authors

Kralik Joakhim

Fabian Kaj

Mjurmann Kristof

Shvajkkert Norbert

Dates

2008-12-10Published

2003-08-01Filed