FIELD: chemistry.
SUBSTANCE: claimed are novel biologically active compounds - derivatives of natural hydroxyamino acids of general formula where R=H or CH3, and X represents anion residue of inorganic acid. Said derivatives represent O-nitroesters of said amino acids and are donors of nitrogen oxide, belonging to group of organic nitrates. Characteristic feature of claimed compounds is that release of nitrogen oxide leads to formation of natural amino acids, harmless for organism, without any by-products. Compounds can be obtained by direct nitrating of hydroxyamino acids in organic solvent and isolated in crystalline state in form of salts with inorganic or organic acids.
EFFECT: improvement of compound obtaining method.
1 cl, 5 ex
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Authors
Dates
2008-12-10—Published
2007-03-21—Filed