METHOD OF PREDICTING OF LIFE EXPECTANCY OF PATIENTS WITH LOCAL CANCER OF PROSTATE Russian patent published in 2008 - IPC A61B10/00 G01N33/74 

FIELD: medicine.

SUBSTANCE: define risk factors from the anamnesis of a life and clinico-laboratory indicators: the age, degree of differentiation of a tumour, level of Testosteron-Depotum and prostates-specific antigen in blood serum (PSA), carry on prediction depending on their values, thus in addition define time from the development of hormone-resistance beginning, estimate level of painful sensations and the general condition of the patient on scale ECOG, define degree of disturbance of an emiction on international IPSS scale, establish gradation and numerical value of risk factors then define life expectancy of the patient in months under the formula: Y=-9.17+0.47•X₁+1.94•X₂-0.698•X₃+0.01•X₄ ²+0.07•X₃ ²-1.66•X₅ ²+1.86•X₆ ²-0.0003•X₇ ²+0.01•X₈ ², where: Y - life expectancy of the patient in months; X_{1, 2...8} - gradation and numerical value of risk factors, and X₁ - age, years; X₂ - tumour differentiation: G₀ - low-grade tumour =0, G₁ differentiated tumour =1, G₂ - moderate-grade tumour =2, G₃ - a low-grade tumour =3, G₄ - an undifferentiated tumour =4; X₃ - Testosteron-Depotum level in ng/ml; X₄ - time from the beginning of hormone-resistance development in months; X₅ - level of painful sensations of the patient: absence of pain =0, mild pain =1, moderate pain d-2, strong pain =3, intolerable pain =4; X₆ - general condition of the patient on ECOG scale: activity of the patient is unlimited =0, restriction by kinds of activity of demanding efforts =1, walking and capable itself to serve, but incapable to perform any work =2, is limited capable for Self-Care =3, completely incapable of any activity =4; X₇ - level of the PSA in ng/ml; X₈ - degree of disturbance of an emiction at patients on international scale IPSS (from 0 to 36 points).

EFFECT: provides possibility of the prediction of life expectancy of patients in months.

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