FIELD: chemistry.
SUBSTANCE: invention relates to specific bifunctional chimeric heterocyclic compounds for targeted destruction of androgen receptors and to their use for producing chimeras aimed at breaking down proteins of androgen receptors, and for producing drugs for treating diseases associated with and regulated by androgen receptors.
EFFECT: obtaining novel compounds which can provide targeted destruction of androgen receptors in prostate cancer cells and inhibit prostate cancer cell proliferation, and have good metabolic stability and pharmacokinetic properties.
7 cl, 1 dwg, 4 tbl, 5 ex
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