BENZOYLPIPERIDINE COMPOUNDS Russian patent published in 2008 - IPC C07D211/32 C07D211/00 A61K31/445 A61P25/18 

FIELD: chemitry.

SUBSTANCE: claimed invention relates to racemic or enantiomerically enriched benzoylpiperidine derivatives, represented with general structural formula (I) , in which n equals 0; and A is selected from group, consisting of phenyl, which can be substituted with one or more similar or different substituents, selected from group, consisting of hydrogen, halogen, normal or branched alkyl with number of carbon atoms from 1 to 4, normal or branched alkoxyl with number of carbon atoms from 1 to 3, nitro, cyano, trifluoromethyl, trifluoromethoxyl, methansulfonyl and phenyl; tienyl; naphtyl; pyridyl; and quinolyl; and n is integer from 1 to 2; and A is selected from group, consisting from phenyl or phenoxyl, which can be substituted with one or more similar or different substituents, selected from group, consisting of hydrogen, halogen, normal or branched alkyl with number of carbon atoms from 1 to 4, normal or branched alkoxyl with number of carbon atoms from 1 to 3, nitro, cyano, trifluoromethyl, trifluoromethoxyl, methanesulfonyl and phenyl; thienyl; naphtyl; pyridyl; and quinolyl; X is selected from group, consisting of O-carbamoyl, imidazole, triazole and carbonate; and Y is selected from group, consisting of hydrogen, halogen, normal or branched alkyl with number of carbon atoms from 1 to 4, normal or branched alkoxyl with number of carbon atoms from 1 to 3, and its pharmaceutically acceptable salts.

EFFECT: creation of compounds for obtaining pharmaceutical compositions for treatment of central nervous system diseases, for instance psychosis and cognitive disease.

29 cl, 1 tbl, 94 ex