FIELD: medicine; pharmacology.
SUBSTANCE: obtain the mixed solution containing oltipraz and soluble polymer in water, for example in the purified water, or insoluble polymer in water in solvent, thus the solvent is organic solvent; and obtaining of solid oltipraz dispersion in polymer. At obtaining of a solid dispersion, the mixed solution can be exposed to spray-type drying at use of the spray-type dryer or granulating at use of the granulator with a fluidised layer.
EFFECT: increase in solubility and biological availability of oltipraz.
18 cl, 2 tbl, 16 ex, 4 dwg
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