METHOD OF OBTAINING NANO-SIZED HYDROXYLAPATITE Russian patent published in 2009 - IPC A61K33/42 A61K33/06 A61K9/10 A61K6/33 A61L27/12 B82B3/00 C01B25/32 

FIELD: chemistry.

SUBSTANCE: nano-sized highly-pure hydroxylapatite (HAP) is obtained in form of alcohol colloid solution (gel), which can be used for production of medicinal preventive preparations in stomatology, for applying bioactive coating on bone implants. Method includes hydroxylapatite synthesis by adding solution of orthophosphoric acid to calcium hydroxide solution and exposure to ultrasound impact, and ethyl or isopropyl alcohol is added to colloid of highly-pure nano-sized hydroxylapatite with concentration from 5% to 40±2% in order to obtain concentration of hydrooxylapatite in alcohol from 0.2 to 20%. After that alcohol mixture is processed with ultrasound with frequency 10-50 kHz during 1-2 hours.

EFFECT: alcohol colloid of nano-sized hydroxylapatite with high stability.

2 cl, 3 ex