FIELD: medicine; pharmacology.
SUBSTANCE: ways of obtaining and pharmaceutical compositions of lipophile association (LA) of ionised pharmaceutical means and one or several lipophile substances are described. LA is in a liquid condition at a room temperature or soluble in solvent with smaller, than at water, dielectric permeability, in the form of solution LA at a room temperature. Solvent, preferably, ethanol, dimethyl carbinol spirit, isopropyl myristate, isopropyl palmitate or glyceride is, LA can be adsorbed or absorbed on the carrier. The carrier is preferably silicified microcrystalline cellulose and-or silicon dioxide. Pharmaceutical means is preferably represented by nicotine.
EFFECT: fast liberation of pharmaceutical means at contact to water at pH, close to physiological and its subsequent delivery in the big circle of blood circulation.
31 cl, 6 dwg, 5 tbl, 5 ex
