NEW CRYSTALLINE STRUCTURES (POLYMORPHIC MODIFICATIONS) SEMICALCIUM SALT OF ATORVASTATIN AND METHODS OF OBTAINING OF THESE AND OTHER POLYMORPHIC MODIFICATIONS OF SALT OF ATORVASTATIN Russian patent published in 2009 - IPC C07D207/34 A61K31/40 A61P9/00 

Abstract RU 2344127 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention concerns new polymorphic modifications of semicalcium of atorvastatin salt by which names Form VI are appropriated, Form VIII, Form IX, Form X, Form XI and Form XII, and to ways of their obtaining, and also ways of obtaining of semicalcium atorvastatin salt polymorphic modifications Form I, Form II, Form IV and Form V, and also amorphous semicalcium atorvastatin salt. Use of new forms in pharmaceutical compositions raises their quality and, thereby, the control over low density lipoproteins level.

EFFECT: provision of the best control over low density lipoproteins level.

61 cl, 26 dwg, 42 ex; 3 tbl

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RU 2 344 127 C2

Authors

Aronkhajm Dzhudit

Lidor-Khadas Remi

Niddam-Khildishejm Valeri

Kovalevski-Ishaj Ehti

Livshits-Liron Rivajtl

Samburski Gaj

Dates

2009-01-20Published

2001-11-29Filed