NOVEL POLYMORPHOUS FORM OF CRYSTALLINE HEMICALCIUM SALT OF ATORVASTATIN Russian patent published in 2011 - IPC C07D207/34 A61K31/40 A61P3/06 

Abstract RU 2409563 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a novel polymorphous form of B-52-crystalline hemicalcium salt of atorvastatin [hemicalcium salt (βR,δR)-2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methlethyl)-3-phenyl-4-{(phenylamino)carbonyl}-1H-pyrrole-1-heptanoic acid] and solvates thereof, having an X-ray diffraction pattern which is essentially identical to that given in dwg.1, with characteristics given in claim 1.

EFFECT: wider field of use of the compounds.

19 cl, 2 tbl, 3 dwg, 7 ex

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RU 2 409 563 C2

Authors

Barkotsi Jozhef

Kotaj Nad' Peter

Shimig D'Jula

Chelen'Jak Judit

Sent-Kirallii Zhuzhanna

Barta Ferents

Katona Zol'Tan

Veretskeine Donat D'Erdi

Nad' Kal'Man

Nemet Norbert

Ruzhich D'Erd'

Dates

2011-01-20Published

2006-04-07Filed