POLYMORPHIC FORMS OF ICOTINIB AND USES THEREOF Russian patent published in 2019 - IPC C07D491/56 A61K31/519 A61P35/00 A61P43/00 

Abstract RU 2710013 C2

FIELD: chemistry.

SUBSTANCE: invention relates to polymorphous form of compound of formula I,

formula I.

Polymorphic form is of form II, and its X-ray powder diffraction pattern has characteristic peaks at diffraction angles 2θ, making 5.5°, 11.0°, 19.7°, 20.9° and 22.6° ± 0.2°. Also disclosed is a method of producing a polymorphous form.

EFFECT: presented polymorphous form II has higher bioavailability.

7 cl, 5 dwg, 1 tbl, 13 ex

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RU 2 710 013 C2

Authors

Hu, Shaojing

Long, Wei

Wang, Fei

Wang, Yinxiang

Ding, Lieming

Dates

2019-12-24Published

2014-06-09Filed