FIELD: medicine; ultrasonic diagnostics.
SUBSTANCE: clinical research is conducted to develop specific medicine forms using polymer microspheres with inserted perfluorocarbon. Medicine forms include microspheres of biologically compatible polymer, preferably with lipids incorporated in polymer, and containing perfluorocarbon, which transits to gaseous form at human body temperature. Patient receives microspheres in effective amount for improvement of ultrasonic imaging of ventricle chambers for longer than 5 minutes, dosage varying from 0.025 to 8.0 mg of microspheres per kg of body weight. Preferable dosage varies from 0.05 to 4.0 mg of microspheres per kg of body weight. Medicine form is usually stored in ampoule. Medicine in dry powder form is recovered with sterile water before application by adding water to ampoule or syringe and shaking it to obtain isosmotic or isotonic microsphere suspension.
EFFECT: improved image of ultrasonic imaging of cardiovascular area for long time period.
33 cl, 5 tbl, 5 ex
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