FIELD: chemistry.
SUBSTANCE: present invention pertains to a new compound - acid mesylate of 4-(4-trans-hydroxycyclohexyl) amino-2-phenyl-7H-pyrrolo [2,3d]pyrimidine and its polymorphous α and β forms. The compound has agonistic activity towards adenosine-1 receptor and can be used for making medicinal preparations for treating hypertensive diseases, congestive heart failure and renal failure.
EFFECT: obtaining a compound with better bioavailability due to high solubility and which is more stable in ambient conditions.
17 cl, 6 dwg, 6 ex
| Title |
Year |
Author |
Number |
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|
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|
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|
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|
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|
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|
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|
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2012 |
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|
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