MONOCYTIC SELF-SPECIFIC CELLS, STIMULATING AUTOTOLERANCE, AND THEIR USE IN PHARMACEUTIAL PREPARATIONS Russian patent published in 2009 - IPC C12N5/08 A61K35/14 A61P37/00 

Abstract RU 2346041 C2

FIELD: chemistry; biochemistry.

SUBSTANCE: present invention pertains to medicine, and particularly to immunotherapy. Proposal is given of a method of obtaining and/or multiplication of monocytic origin self-specific regulatory T-cells, co-expressing CD3 and CD14 antigens on their surface. The cells are suitable for preventing and/or curing diseases, caused by violation of self-tolerance, particularly, auto-immune diseases and allergies, as well as for production of pharmaceutical preparations. The given cells are self-specific for a patient, on which they are used.

EFFECT: design of a method of obtaining and/or multiplication of monocytic origin self-specific regulatory T-cells.

38 cl, 9 ex, 4 tbl, 12 dwg

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RU 2 346 041 C2

Authors

Kremer Bernd Karl Fridrikh

Fendrikh Fred

Shul'Tse Maren

Dates

2009-02-10Published

2004-01-09Filed