FIELD: chemistry; pharmacy.
SUBSTANCE: invention concerns novel compounds of formula I 
, where X1 is O; Ar1 is aryl optionally substituted by one or more halogen atoms; R1 is alkoxyalkyl, alkyl, cycloalkyl, cycloalkylalkyl, hydroxyalkyl, tetrahydropyranyl or piperidinyl optionally substituted by -S(O)2 alkyl group; and R2 is hydroxyalkyl or oxoalkyl. Also invention concerns composition for kinase p38 induced disease control or prevention.
EFFECT: obtaining novel bioactive compounds for kinase p38 induced disease control or prevention.
4 cl, 10 ex, 2 tbl
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