METHOD OF WATER BALANCE DISORDER DIAGNOSTICS AND TREATMENT FOR PREGNANT WOMEN Russian patent published in 2009 - IPC A61B10/00 A61K31/718 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention concerns medicine, obstetrics and rehabilitation and can be applied in diagnostics and treatment of water balance disorder for pregnant women. Water balance disorder type is defined for patient. For I type characterised by 'empty' vessels and hydropic interstition, hypokinetic blood circulation type, average venous hematocrit indicators of 39% or over, low average peripheral hematocrit indicators of 34% or lower and hematocrit indicator difference over 3%, differentiated infusion therapy is performed, with infusion therapy volume calculated with account of circulation blood volume (CBV) increase expected for healthy woman at second or third trimester, equal to 40% or 30% respectively, and of indicators of dependency between original body weight before pregnancy and infusion therapy volume rated per 1 kg of body weight by nomogram No 3. Infusion therapy includes 10% refortan in dosage selected for each pregnant woman with account of her original body weight and pregnancy term by nomogram No 2 and glucose and magnesium mix in amount of 400 ml: 325 ml of 20% glucose solution and 75 ml of 25% magnesium sulfate solution. Infusion therapy volume is calculated so as liquid volume combined with water consumed in one day time comprises normal CBV increase for second or third trimester. For II type characterised by 'empty' vessels and 'dry' interstition, transsudate presence in peritoneal cavity, uterus and parenchymic tissue edema, hyperkinetic blood circulation type, venous and peripheral hematocrit indicators of over 43% and 42% respectively and their difference not larger than 2%, infusion therapy similar to that of I type is performed, with addition of saline solution in volume corresponding to water-binding properties of 10% refortan. For III type characterized by total hyperhydration, hypo- or hyperkinetic blood circulation type, average venous and peripheral hematocrit indicators of under 35% and 33% respectively and their difference not larger than 2%, dehydration therapy by lasiks and euphillin microdosage is performed, III type is transformed into I type, and infusion therapy corresponding to I type is performed with a single difference in total liquid volume administered in one day time, reduced in connection to hypervolemia by value equal to water amount, which can be drawn to vessel course by refortan.

EFFECT: improved treatment results for pregnant patients with water balance disorder by development of differentiated infusion therapy with account of pathological water and original body weight redistribution type both before and after labour, thus reducing number of lethal outcome.

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