THIOMORPHOLINE DERIVATIVES OF STEROIDS, THEIR USE IN MAKING MEIOSIS REGULATING MEDICINAL PREPARATIONS AND METHOD OF PRODUCING THESE COMPOUNDS Russian patent published in 2009 - IPC C07J43/00 C07J73/00 A61K31/58 A61P15/08 

Abstract RU 2349597 C2

FIELD: chemistry.

SUBSTANCE: description is given of thiomorpholine derivatives of steroids with general formula I . These steroids are characterised by presence of a thiomorpholine fragment, bonded to a C17 steroid skeleton through an alkylene spacer, where R4 and R4' are hydrogen and methyl, under the condition that, both R4 and R4' represent hydrogen at the same time.

EFFECT: invention can be successfully used for stimulating meiosis of human oocyte.

12 cl, 2 ex, 5 tbl, 6 dwg

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RU 2 349 597 C2

Authors

Blume Torsten

Lindental' Bernkhard

Prelle Katja

Peters-Kottig Mikhaehle

Dates

2009-03-20Published

2004-07-13Filed