COMPOSITION FOR FERTILIZATION IN VITRO Russian patent published in 2005 - IPC

Abstract RU 2263516 C2

FIELD: medicine.

SUBSTANCE: the present innovation deals with composition for fertilization in vitro and the system for its delivering (device). The composition suggested contains steroid at the quantity of below 5% (weight/weight), that is: 4.4-dimethyl-5α-cholesta-8.14.24-trien-3β-ol, hemisuccinate of 4.4-dimethyl-5^α-cholest-8.14.24-trien-3^β-ol; 5^α-cholest-8.14-dien-3^β-ol; hemisuccinate of 5^α-cholest-8.14-dien-3^β-ol; (20S)-cholest-5-en-3, 20-diol; N-(methionine)amide of 3^β-hydroxy-4.4-dimethyl-5^α-chol-8.14-dien-24-oic acid or cholest-5-en-16^β-ol, and, also, additive (water-soluble protein or phosphoglyceride). Delivering system has got either one foramen or one cavity that contains the composition mentioned as a solid product or solution. The composition of sterols contains no constituents negatively affecting oocytes and could be dissolved in aqueous medium without physical impact (that is, heating, mixing or ultrasound treatment).

EFFECT: higher efficiency of fertilization in vitro.

8 cl, 5 ex, 3 tbl

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RU 2 263 516 C2

Authors

Andersen Tina Mejnerts

Dates

2005-11-10—Published

2000-09-11—Filed