FIELD: medicine.
SUBSTANCE: declared invention concerns a chemical-pharmaceutical industry and antagonist P2X7 of a receptor and concerns a pharmaceutical product for treatment of the arthritis containing bond 
, representing, and specified antagonist P2X7 of a receptor represents adamanthyl derivative, and the second active ingredient which represents an inhibitor of the factor of a necrosis tumours αTNFα).
EFFECT: declared invention provides accurately expressed favorable anti-inflammatory effect and pain weakening.
8 cl, 3 ex, 1 tbl
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2004 |
- Bafton-Smit Najdzhel
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| DERIVATIVES OF ADAMANTANE, METHOD FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION AND METHOD FOR PREPARING PHARMACEUTICAL COMPOSITION |
1998 |
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2000 |
- Al'Kara Lilian
- Kehffri Moja
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- Mortimor Majkl
- Pimm Osten
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RU2272025C2 |
| DERIVATIVES OF ADAMANTANE, METHOD FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHODS FOR TREATMENT |
2000 |
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1998 |
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RU2197477C2 |
| NOVEL COMPOUNDS |
2001 |
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| DERIVATIVES OF PIPERIDINE, METHODS FOR THEIR PREPARING AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
2001 |
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RU2298550C2 |
| 8-CARBAMOYL-2-(2,3-DI-SUBSTITUTED PYRID-6-YL)-1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES AS APOPTOSIS-INDUCING AGENTS FOR CANCER TREATMENT |
2012 |
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| SPIROPYRAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF, METHOD FOR MODULATION OF OPIOID RECEPTOR AND METHOD FOR TREATMENT USING SUCH COMPOUNDS |
2002 |
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2008 |
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