FIELD: medicine, pharmaceutics.
SUBSTANCE: present invention refers to selective sigma-receptor ligands possessing prototypical biphase, antiapoptotic and proapoptotic activity in relation to normal neuronal and cancer cells, to a pharmaceutical composition based thereon, and to using the same for preparing the respective pharmaceutical products.
EFFECT: preparing the pharmaceutical products with anticancer, antimetastatic, anti-inflammatory, neuroprotective, anticonvulsant, antidepressive and nootropic analeptic or sedative action.
4 cl
Title | Year | Author | Number |
---|---|---|---|
PHARMACEUTICAL COMPOSITION, CONTAINING ANTAGONIST P2X OF RECEPTOR AND FACTOR OF TUMOUR NECROSIS α | 2004 |
|
RU2350354C2 |
PHARMACEUTICAL COMPOSITION, CONTAINING ANTAGONIST OF P2X-RECEPTOR AND NONSTEROID ANTIINFLAMMATORY MEDICAL PRODUCT | 2004 |
|
RU2338556C2 |
DERIVATIVES OF ADAMANTANE, METHOD FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHODS FOR TREATMENT | 2000 |
|
RU2254333C2 |
DERIVATIVES OF ADAMANTANE, METHODS FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS PREPARING, METHODS FOR TREATMENT OF RHEUMATIC ARTHRITIS AND LUNG CHRONIC OBSTRUCTIVE DISEASE | 2000 |
|
RU2272025C2 |
DERIVATIVES OF ADAMANTANE, METHOD FOR THEIR PREPARING, PHARMACEUTICAL COMPOSITION AND METHOD FOR PREPARING PHARMACEUTICAL COMPOSITION | 1998 |
|
RU2214997C2 |
PYRAZOLONE DERIVATIVES | 2006 |
|
RU2407737C2 |
ANTIBODIES TO B7-H3 AND CONJUGATES OF ANTIBODY AND DRUG | 2017 |
|
RU2764651C2 |
SIGMA-LIGANDS FOR APPLICATION IN PREVENTION AND/OR TREATMENT OF POSTOPERATIVE PAIN | 2011 |
|
RU2569055C2 |
SIGMA-RECEPTOR INHIBITORS | 2005 |
|
RU2404972C2 |
8-CARBAMOYL-2-(2,3-DI-SUBSTITUTED PYRID-6-YL)-1,2,3,4-TETRAHYDROISOQUINOLINE DERIVATIVES AS APOPTOSIS-INDUCING AGENTS FOR CANCER TREATMENT | 2012 |
|
RU2625315C2 |
Authors
Dates
2013-11-10—Published
2008-01-14—Filed