SOLID NANOCOMPOSITION FOR DELIVERY OF BIOLOGICALLY ACTIVE SUBSTANCES Russian patent published in 2009 - IPC A61K36/15 A61K31/35 A61K31/715 A61K31/79 A61K47/30 A61P43/00 

FIELD: nanotechnologies; pharmaceutics.

SUBSTANCE: invention is related to food and pharmaceutical industry, namely to solid nanocompositions. Invention Solid nanocomposition contains 0.1-15% of active component, 40-95% of polymer, 0-6% hydrophobic or inertial polymer and 0-56% water-soluble component, at that nanocomposition on the basis contains taxipholin as active component, 40-95% of polymer, such as arabinogalactan or polyethylene glycols or polyvinyl pyrrolidones or polyvinyls of different molecular weights, and also 0-56% of water soluble polymer selected from row of possible fillers: kollidon VA64 (copolymer of vinylpyrrolidone and vinyl acetate), ludipress (modified lactose), kollidon 90F (high molecular polyvinyl pyrrolidone with molecular weight of 1000000- 1500000), sugar powder, isomaltose, 0-6% of hydrophobic or inertial polymer, where hydrophobic component contained by nanocomposition is compritol 888 ATO, (composition of mono-, di- and triglycerides of behenic acid), and inertial component is kollidon SR, Bast (mixture of polymers of polyvinyl pyrrolidone and polyvinyl acetate).

EFFECT: provides for higher bioavailability of active substances introduced in nanocomposition at creation of solid dosed forms with controlled release.

4 cl, 16 ex, 6 dwg