WATER-SOLUBLE COMPOSITION, POSSESSING ANTI-TUMOUR ACTIVITY AND METHOD FOR OBTAINING THEREOF Russian patent published in 2017 - IPC A61K31/122 A61K31/215 A61K31/277 A61K47/30 A61K47/12 A61K47/18 A61P35/00 

FIELD: medicine.

SUBSTANCE: composition contains, wt %: soloxolon methyl 4.0-40.0; PEG with molecular weight 4000 Da - 40.0-57.4; β-glycine - 10.0-56.0. The invention also deals with method for obtaining composition, the method includes dissolution of soloxolon methyl and PEG in tert-butyl alcohol with ultrasonic impact and simultaneous heating of mixture to 45-50°C for 5-30 minutes until components are completely dissolved, after that addition of β-glycine and re-exposure of mixture to ulrrasound for 7-10 min, freezing and exposure of the obtained suspension at temperature -20°C for 4 hours, with the following lyophilic drying first at temperature -20°C until pressure in chamber drops lower than 17 mtorr, then at temperature 30°C for 2 hours.

EFFECT: increase of water-solubility and anti-tumour activity of composition.

2 cl, 3 dwg, 2 tbl, 7 ex