MEDICATION, CONTAINING FGF2 AS ACTIVE INGREDIENT, FOR TREATMENT OR PREVENTION OF ASTHMA AND CHRONIC OBSTRUCTIVE LUNG DISEASES Russian patent published in 2009 - IPC A61K38/18 A61K38/19 A61K38/20 A61K38/21 A61P11/06 

Abstract RU 2351356 C2

FIELD: medicine.

SUBSTANCE: medication for treatment and prevention of asthma contains FGF2 (fibroblast growth factor-2) as active ingredient, asthma being caused by overexpression of IL-13 (interleikin-13) or overexpression of IFN-γ (interferon-γ), where FGF2 inhibits IL-13 activity, FGF2 inhibits VEGF activity and FGF2 inhibits TGF-β1 activity (transforming growth factor-β1). Medication for treatment or prevention of chronic obstructive lung disease (COLD), containing FGF2 (fibroblast growth factor-2) as active ingredient, where chronic obstructive lung disease (COLD) is caused by overexpression of IFN-γ (interferon-γ). Inhibitor of IL-13 activity, containing FGF2 (fibroblast growth factor-2) as active ingredient. Inhibitor of VEGF activity, containing FGF2 (fibroblast growth factor-2) as active ingredient. Inhibitor of TGF-β1 activity, containing FGF2 (fibroblast growth factor-2) as active ingredient.

EFFECT: prevention of asthma and COLD.

8 cl, 31 dwg, 7 ex

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RU 2 351 356 C2

Authors

Kim Joon-Keun

Kang Soo Khiung

Kim Biong Moon

Son Mivon

Dates

2009-04-10Published

2005-05-12Filed