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(19)

RU

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2 352 337

(13)

C2

(51)

IPC

A61K31/44(2006-01-01)

A61K31/47(2006-01-01)

A61P27/02(2006-01-01)

(21) (22)

Application

2005118107/14, 2003-10-30

(24)

Start date

2003-10-30

(22)

Actual filing date

2003-10-30

(45)

Published

2009-04-20

(72)

Inventor

Klimko Piter G.Bingamehn Dehvid P.

(73)

Holder

Al'Kon, Ink.

INHIBITORS OF HISTONDEACETYLASE FOR TREATMENT OF OPHTHALMOLOGIC NEOVASCULAR DISTURBANCES AND DISEASES Russian patent published in 2009 - IPC A61K31/44 A61K31/47 A61P27/02 

Abstract RU 2352337 C2

FIELD: medicine.

SUBSTANCE: invention concerns medicine, in particular, ophthalmology, and concerns inhibitions of neovascularisation of retina. For this purpose it is offered to use derivative of hydroxamic acid, chosen of suberoylanilide hydroxamic acid (SAHA), Trichostatin A, and/or Scriptaid.

EFFECT: chosen derivatives provide effective inhibition of the VEGF-induced proliferation and life expectancy of endothelial cells of a retina.

5 ex, 1 tbl

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RU 2 352 337 C2

Authors

Klimko Piter G.

Bingamehn Dehvid P.

Dates

2009-04-20—Published

2003-10-30—Filed

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