PEPTIDES FOR INHIBITING ANGIOGENESIS Russian patent published in 2019 - IPC C07K7/06 C07K7/08 A61K38/08 A61K38/10 A61P35/00 A61P27/00 

Abstract RU 2708375 C2

FIELD: chemistry.

SUBSTANCE: invention relates to use of peptides containing amino acid sequence KFARLWTEIPTAIT (SEQ ID NO: 1), FTEIPTI (SEQ ID NO: 3), for inhibiting angiogenesis and treating disorders associated with VEGF-induced vascular permeability, where the patient suffers from visual impairment or vision loss (blindness), macular degeneration, retinal central retinal occlusion, retinal vein occlusion, proliferative diabetic retinopathy, neovascular macular degeneration (NMD), premature retinopathy, ischemic retinopathy, intraocular neovascularisation, corneal neovascularisation, retinal neovascularisation, choroid neovascularisation, diabetic macular oedema, diabetic retinal ischemia, diabetic retinal oedema and proliferative diabetic retinopathy, iris palpebral iris, neovascular glaucoma, retinoblastoma, uveitis and corneal graft neovascularization.

EFFECT: disclosed are peptides for inhibiting angiogenesis.

20 cl, 12 dwg, 5 tbl, 10 ex

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RU 2 708 375 C2

Authors

Komarova Yulia A.

Rosenblatt Mark

Malik Asrar B.

Dates

2019-12-06Published

2016-03-02Filed