METHOD OF TREATING OPHTHALMIC ANGIOGENESIS, RETINAL OEDEMA, RETINAL ISCHEMIA AND DIABETIC RETINOPATHY WITH USING SELECTIVE RTK INHIBITORS Russian patent published in 2012 - IPC A61K31/506 A61P27/02 A61F9/00 

Abstract RU 2445096 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely ophthalmology, and can be used for ensuring regression of ocular neovascularisation. That is ensured by introducing a composition containing a therapeutically effective amount of a receptor tyrosine kinase inhibitor which blocks tyrosine autophosphorylation of VEGF receptor-2 with IC50≤ 10 nM and VEGF receptor-1 with 1C50≤ 10 nM and PDGFR with 1C50≤ 100 nM.

EFFECT: invention provides strong antiangiogenic effectiveness, ensured avoiding visual acuity loss related to ocular neovascularisation.

7 cl, 5 tbl, 8 ex, 9 dwg

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RU 2 445 096 C2

Authors

Bingamehn Dehvid P.

Dates

2012-03-20Published

2006-02-23Filed