FIELD: pharmaceuticals.
SUBSTANCE: invention relates to new pyrazine compounds of Formula I, where A, B, R1, R2, V, W, X, Y, m, n are defined in the claims and act specifically on adenosine receptors, in particular on A2a. The invention also relates to pharmaceutical compositions containing one or more compounds as an active ingredient, and the use of these compounds in the treatment of diseases associated with adenosine receptors (AR), for example cancer, such as non-small cell lung cancer (NSCLC), renal cell carcinoma (RCC), prostate cancer and breast cancer.
EFFECT: obtaining pyrazine compounds and their use.
47 cl, 4 tbl, 308 ex
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Authors
Dates
2023-12-14—Published
2019-08-16—Filed