[1,2,4]OXADIAZOLES (VERSIONS), METHODS OF OBTAINING THEM, PHARMACEUTICAL COMPOSITION AND METHOD OF INHIBITING ACTIVATION OF METABOTROPIC GLUTAMATE RECEPTORS - 5 Russian patent published in 2009 - IPC C07D413/12 C07D413/14 C07D417/14 C07D471/04 A61K31/4245 A61K31/421 A61K31/42 A61P25/00 

Abstract RU 2352568 C9

FIELD: chemistry.

SUBSTANCE: described is novel compound of formula (I)

or its pharmaceutically acceptable salt, values of radicals are given in invention formula Compound has ability to inhibit receptor mGluR5, which intends it for prevention and/or treatment of receptor mGluR5- associated disturbances. Also described is pharmaceutical composition, method of inhibiting activation of receptors mGluR5, using compound of formula (I). Described is method of obtaining compound of formula 1a or 1b structure.

EFFECT: increasing output of suitable product.

18 cl, 825 ex

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RU 2 352 568 C9

Authors

Arora Dzhalaj

Val'Dman Magnus

Vensbo David

Ingve Ul'Rika

Isaak Metvin

Jokhansson Martin

Jjubakk Khelena

Kers Anika

Makled Donal'D Eh.

Malberg Jokhan

Minidis Aleksander

Oskarsson Karin

Ostervall' Kristoffer

Sin' Tao

Slassi Abdel'Malik

Stefanats Tomislav

Stormehn Tomas M.

Ehdvards Luiza

Dates

2009-04-20Published

2003-08-08Filed