FIELD: medicine.
SUBSTANCE: invention relates to medicine and biochemistry and concerns compositions for stabilisation of protein active ingredients in pharmaceutical preparations, which contains two following components: a) surface-active substance, preferably non-ion detergent (tenzid), and b) mixture of four amino acids: glutaminic acid (Glu), glutamine (Gln), aspartic (Asp) and asparagine (Asn).
EFFECT: synergetic effect at combined using of said four concrete amino acids.
10 cl, 11 ex, 6 dwg
Title |
Year |
Author |
Number |
COMPOSITION FOR PROTEIN PHARMACEUTICAL PREPARATION WITH NO ADDED HUMAN SERUM ALBUMIN (HSA) |
2004 |
|
RU2491927C2 |
Liquid composition containing botulinum toxin and a stabilizing agent, and a method for its preparation |
2017 |
- Lee, Chee Gun
- Oum, Ji Khyun
|
RU2748653C2 |
LIQUID PHARMACEUTICAL COMPOSITION OF BOTULINUM TOXIN |
2008 |
- Dzjung Khun Kho
- Jang Gi Khueok
- Kim Khak Voo
- Voo Khee Dong
- Rkhee Chang Khoon
|
RU2440825C2 |
LIQUID COMPOSITION STABILIZING BOTULINUM TOXIN |
2019 |
- Kim, Wanseop Paul
- Kim, Yeong-Mok
- Park, Gi-Sik
- Park, Jae-Min
- Lee, Ae-Yeon
|
RU2812790C2 |
LIQUID COMPOSITION OF NEUROTOXIN STABILIZED WITH TRYPTOPHAN OR TYROSINE |
2017 |
- Yarstad, Anders
- Friis, Anna
- Shtal, Ulf
- Gurell, Ann
- Agren, Barbro
- Edstrom, Emiliya
- Pikett, Endryu
|
RU2741497C2 |
STABILIZED NON-PROTEIN COMPOSITIONS OF CLOSTRIDIAL TOXIN |
2017 |
- Abiad Maurice
- Dani Bhas
- Shalaev Evgenyi
|
RU2762607C2 |
CLOSTRIDIAL NEUROTOXINS WITH MODIFIED PERSISTENCE |
2009 |
|
RU2524429C2 |
PROTEIN STABILISATION FORMULATION FREE FROM MAMMALIAN EXCIPIENTS |
2010 |
- Tehjlor Kharol'D
- Burger Markus
- Mander Gerd J.
|
RU2539388C2 |
PHARMACEUTICAL STRUCTURE CONTAINING BOTULINUM NEUROTOXIN |
2005 |
- Vebb Pol
- Vajt Mehri
- Partington Dzhulii
|
RU2407541C2 |
METHOD OF PRODUCING PROTEOLYTICALLY PROCESSED POLYPEPTIDE |
2012 |
|
RU2673910C2 |