FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to pharmaceutics and medicine, and concerns protein and peptide stabilisation formulation which contains a hydrophilic polymer, a mixture of polyalcohol and sugar, wherein a weight ratio of polyalcohol to sugar makes from 2:1 to 5:1 (wt %), a detergent, and wherein the formulation is free from stabilising proteins. A composition and a kit for treating a disease or a composition caused by hyperactive cholinergic innervation of muscles or endocrine glands in a patient, and contain the above formulation and peptide, protein or a mixture thereof.
EFFECT: group of inventions provides the better protein stability in the absence of stabilising proteins.
13 cl, 4 ex
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Authors
Dates
2015-01-20—Published
2010-04-16—Filed