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2 356 577

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IPC

A61K39/02(2006-01-01)

A61K39/05(2006-01-01)

G01N33/53(2006-01-01)

(21) (22)

Application

2005115837/13, 2003-10-22

(24)

Start date

2003-10-22

(22)

Actual filing date

2003-10-22

(45)

Published

2009-05-27

(72)

Inventor

Khoffman Stefen L.Uang RuobingEhpshtejn Dzhudit E.Kokhen Dzhozef D.

(73)

Holder

Glaksosmitklajn Bajolodzhikals S.A.Soedinennye Shtaty Ameriki, Predstavlennye Ministrom Voenno-Morskikh Sil

METHODS OF MALARIA VACCINATION Russian patent published in 2009 - IPC A61K39/02 A61K39/05 G01N33/53

Abstract RU 2356577 C9

FIELD: biotechnology.

SUBSTANCE: invention concerns biotechnology and medicine. Claimed method involves priming of immune response to malaria by DNA-based vaccine and response stimulation by protein-based vaccine. Invention claims vaccine including priming composition of at least one polynucleotide encoding at least one first anti-malaria antigen, and stimulating composition of at least one polypeptide activating additionally at least one second anti-malaria antigen. Also invention concerns human immunisation kit for malaria-inducing pathogen.

EFFECT: expanded immune response due to recurrent immunisation (stimulation) by protein-based vaccine.

44 cl, 7 ex, 12 dwg, 5 tbl

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RU 2 356 577 C9

Authors

Khoffman Stefen L.

Uang Ruobing

Ehpshtejn Dzhudit E.

Kokhen Dzhozef D.

Dates

2009-05-27—Published

2003-10-22—Filed