COMPOUNDS, WHICH ARE ACTIVE TOWARDS RECEPTORS, ACTIVATED BY PEROXISOME PROLIFERATOR Russian patent published in 2009 - IPC C07D209/42 C07D231/56 C07D471/04 A61K31/404 A61K31/416 A61K31/437 A61P3/04 A61P3/06 

FIELD: chemistry, pharmacology.

SUBSTANCE: present invention relates to compounds with formula I, active towards receptors, activated by peroxisome proliferators (PPAR), and can be used in medicine, formula I, where U, W, X and Y represent CH, V represents CR⁸; R¹ represents-C(O)OR or a carboxylic acid isoster, where R is a hydrogen atom, substituted alkyl, aryl or heteroaryl; R² represents -S(O)₂R²¹; R⁶ and R⁷ represent a hydrogen atom, substituted alkyl or cycloalkyl; R⁸ represents a hydrogen atom, halogen, -OR⁹, substituted inferior alkyl, cycloalkyl, heterocycloalkyl, phenyl, benzyl, heteroaryl or heteroaralkyl; R⁹ represents a substituted alkyl or cycloalkyl; R²¹ represents a substituted heteroaryl or phenyl; n equals 1.

EFFECT: obtaining new biologically active compounds and pharmaceutically active compositions based on these compounds.

46 cl, 134 ex, 4 tbl