FIELD: medicine; pharmacology.
SUBSTANCE: invention is related to 4-pyperazinyl-benzen-sulfanylindols with the general formula I , where: R1 and R2 each independently means hydrogen, halogen, alcoxy, R3 and R4 each independently means hydrogen, halogen, alkyl, n is equal to 0 to 4, R6 in each particular case means hydrogen or halogen, R7 and R8 each means hydrogen, R9 means hydrogen, alkyl, or individual isomer, racemic or non-racemic mixture of isomers or their pharmaceutically acceptable salt or solvate. The pharmaceutical compositions are described based on compound I.
EFFECT: compounds can be efficiently used in treatment of certain diseases of central nervous system.
14 cl, 1 tbl, 4 ex
Title | Year | Author | Number |
---|---|---|---|
INDOLE DERIVATIVES SHOWING AFFINITY TO 5-HT RECEPTORS | 2002 |
|
RU2294932C2 |
2,5-SUBSTITUTED TETRAHYDROISOQUINOLINE AND A PHARMACEUTICAL MODULATION COMPOSITION 5-НТ6 | 2004 |
|
RU2327689C2 |
QUINOLINE/BENZOXAZINONE DERIVATIVES AND THEIR APPLICATION | 2004 |
|
RU2333204C2 |
BENZIMIDAZOLE AND INDOLE DERIVATIVES AS SELECTIVE 5-HT6 AND/OR 5-HT2A RECEPTOR ANTAGONISTS | 2006 |
|
RU2415138C2 |
CHROMAN DERIVATIVES AND APPLICATIONS THEREOF IN TREATING CNS DISORDERS | 2005 |
|
RU2396266C2 |
BENZOXAZINE DERIVATIVES AND THEIR APPLICATION | 2004 |
|
RU2354651C2 |
N-PHENYL-2-PYRIMIDINE DERIVATIVES | 2003 |
|
RU2370493C2 |
AMINOALCOXYINDOLES, AS LIGANDS OF 5-NT6 RECEPTOR, FOR TREATMENT OF CNS DISEASES | 2003 |
|
RU2350602C2 |
TETRALINE AND INDAN DERIVATIVES AND APPLICATION THEREOF | 2005 |
|
RU2396255C2 |
DERIVATIVES OF HETEROARYLALKYLPIPERAZINE AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 2001 |
|
RU2243970C1 |
Authors
Dates
2008-05-20—Published
2003-10-13—Filed