COMBINATIONS OF ACTIVATOR (ACTIVATORS) OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR), AND INHIBITOR (INHIBITORS) OF STEROL ABSORPTION AND TREATMENT OF VASCULAR DISEASES Russian patent published in 2013 - IPC A61K31/397 A61P9/00 

Abstract RU 2483724 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to field of pharmaceutics and medicine and deals with pharmaceutical composition or therapeutic combination for treatment of vascular pathological states, diabetes, obesity and reduction of concentration of sterols in plasma, which include: (a) at least, one activator of peroxisome proliferator-activated receptor, selected from group, consisting of fenofibrate, clofibrate, gemfibrozil, cyprofibrate, bezafibrate, clinofibrate, binifibrate, lifibrole or their mixture, and (b) sterol absorption inhibitor, represented by formula

, or its pharmaceutically acceptable salt.

EFFECT: claimed are combinations of activator (activators) of peroxisome proliferator-activated receptor (ppar), and inhibitor (inhibitors) of sterol absorption and treatment of vascular diseases.

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RU 2 483 724 C2

Authors

Kosoglou Teddi

Dehvis Garri R.

Pikar Zhill' Zhan Bernar

Sho Ving-Ki Filip

Dates

2013-06-10Published

2008-11-14Filed