HETEROCYCLIC COMPOUNDS AND APPLICATION METHODS Russian patent published in 2009 - IPC C07D207/48 C07D209/12 C07D401/12 C07D403/12 C07D417/12 A61K31/40 A61P3/04 A61P3/06 A61P3/10 

FIELD: chemistry.

SUBSTANCE: present invention pertains to new compounds with formula I: , where L represents radical , in which R₁ represents H, C_1-4alkyl; n represents 0 or 1; or L represents radical , in which R₁ represents H, C_1-4alkyl; m equals 1; R represents H, halogen, C₁-C₄alkyl or C₁-C₄-alkoxy; Z represents a bond, -C(O)NH-, O or S; p is an integer from 1 to 5; Q represents a bond with the condition that, Z is not a bond, when p equals 1; or represents O, S or -C(O)NR₆-, where R₆ represents H, C_1-4alkyl or C_3-6cycloalkyl; or W and R₆ together with a nitrogen atom, to which they are bonded, form or or Q represents -NR₆-, or in the condition that, p is not equal to 1; W represents , , , , ,

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.

EFFECT: obtaining compounds with agonistic activity towards PPAR receptors, which enables them to be used in pharmaceutical compositions and methods of treating conditions, mediated by these receptors.

12 cl, 7 ex