DISPERSE ACTIVATOR FOR HIGH-INTENSITY FOCUSED ULTRASONIC THERAPY AND ITS APPLICATION Russian patent published in 2009 - IPC A61K49/22 A61K9/127 A61K31/685 

FIELD: medicine.

SUBSTANCE: present invention discovers a disperse activator for high-intensity focused ultrasound therapy (HIFUS therapy). The activator comprises a disperse phase consisting of a nucleus material encapsulated with a membrane-forming material, and a dispersive phase consisting of the aqueous medium. The disperse phase is regularly dispersed in the dispersive phase, while the particle size of the disperse phase is within 0.1-8 mcm; amount of the membrane-forming material in an activator is 0.1-100 g/l; the nucleus material consists of liquid not undergoing a liquid-gas transition within 38-100°C, and amount of the nucleus material in the activator is 5-200 g/l. According to the present invention, the disperse activator for HIFUS therapy can change considerably the acoustic environment in position of a target with improving deposition of acoustic energy in position of a target during HIFUS therapy. Besides, the invention discovers application of the disperse activator for HIFUS therapy during HIFUS therapy.

EFFECT: essentially improved possibilities for clinical essentially improve in removing the malignant cells.

18 cl, 4 ex, 4 tbl