EMBALOGENIC MATRIX DECOMPOSITION METHOD IN EXPERIMENT Russian patent published in 2020 - IPC G09B23/28 

Abstract RU 2739669 C1

FIELD: medicine.

SUBSTANCE: invention refers to experimental medicine, neurology and can be used for destruction of embalogenic (EM) matrix in experiment. That is ensured by simulating thrombosis of a middle cerebral artery by means of EM obtained from arterial blood of rabbits in vitro, followed by imaging of MRI and angiography. After imaging of EM rabbit Omnipak is introduced in amount of 20 ml through installed in the right common carotid artery catheter, followed by transcranial exposure on EM of low-intensity ultrasound of power 30 kW and frequency 40 kHz for 2 minutes.

EFFECT: method enables increasing the destruction efficiency of EM in ischemic stroke with reducing the local ultrasound cavitation energy level due to loosening and EM Omnipac strength reduction.

1 cl, 1 ex

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RU 2 739 669 C1

Authors

Maistrenko Dmitrii Nikolaevich

Granov Dmitrii Anatolevich

Nikolaev Dmitrii Nikolaevich

Generalov Mikhail Igorevich

Oleshchuk Anna Nikitichna

Molchanov Oleg Evgenevich

Stanzhevskii Andrei Alekseevich

Kokorin Denis Mikhailovich

Maistrenko Aleksei Dmitrievich

Popova Alena Aleksandrovna

Ivanov Aleksandr Sergeevich

Evtushenko Vladimir Ivanovich

Zverev Dmitrii Anatolevich

Dates

2020-12-28Published

2020-08-17Filed