FIELD: medicine.
SUBSTANCE: invention refers to experimental medicine, neurology and can be used for destruction of embalogenic (EM) matrix in experiment. That is ensured by simulating thrombosis of a middle cerebral artery by means of EM obtained from arterial blood of rabbits in vitro, followed by imaging of MRI and angiography. After imaging of EM rabbit Omnipak is introduced in amount of 20 ml through installed in the right common carotid artery catheter, followed by transcranial exposure on EM of low-intensity ultrasound of power 30 kW and frequency 40 kHz for 2 minutes.
EFFECT: method enables increasing the destruction efficiency of EM in ischemic stroke with reducing the local ultrasound cavitation energy level due to loosening and EM Omnipac strength reduction.
1 cl, 1 ex
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Authors
Dates
2020-12-28—Published
2020-08-17—Filed