NUETRALISING ANTIBODIES AGAINST GDF-8 AND THEIR APPLICATION Russian patent published in 2009 - IPC C07K16/22 C12N15/13 C12N15/70 A61K39/395 

Abstract RU 2360925 C2

FIELD: chemistry, medicine.

SUBSTANCE: novel antibodies and fragments of human antibodies are bound with GDF-8 in a specific way and inhibit its activity in vitro and/or in vivo. On the basis of said invention pharmaceutical composition is created, which can be used for diagnostics, prevention or treatment of degenerative dysfunctions of muscle or bone or disorders of insulin metabolism.

EFFECT: extending range of arsenal of technical means used in treatment of diseases related to muscular, bone tissue or insulin metabolism.

Similar patents RU2360925C2

Title Year Author Number
IMPROVED ANTIBODIES GDF-8 ANTAGONISTS AND THEIR USE 2013
  • Epger Dzhejms Rizoner
  • Mejder Mishel Mari
  • Perris Kevin Delos
RU2630634C2
ANTIBODIES AGAINST HUMAN GDF8 2011
  • Stitt Trevor
  • Latres Ehster
RU2567805C2
GDF8 HUMAN ANTIBODIES 2011
  • Stitt Trevor
  • Latres Ester
RU2710156C2
APPLYING MYOSTATIC INHIBITORS (GDF8) IN COMBINATION WITH CORTICOSTEROIDS FOR TREATING NERVOUS-MUSCULAR DISEASES 2004
  • Uittmor Lajz-Ehnn
  • Li Sjanpin
RU2322261C2
IL-6 ANTAGONISTS AND USES THEREOF 2013
  • Shmidt Majkl M.
  • Erbe Devid V.
  • Barns Tomas M.
  • Ferfajn Erik Stiven
  • Tisdejl Elison
RU2670943C9
ANTIBODIES AGAINST PD-1 AND THEIR USE 2018
  • Yang, Yi
  • Xie, Jingshu
  • Dong, Chunyan
  • Yang, Fang
  • Lu, Chengyuan
  • Cheng, Xiaodong
  • Shen, Yuelei
  • Ni, Jian
  • Guo, Yanan
  • Chen, Yunyun
RU2788616C2
NEUTRALIZING BINDING MOLECULES DIRECTED AGAINST INFLUENZA VIRUS, AND METHODS OF THEIR APPLICATION 2016
  • Kallewaard-Lelay, Nicole
  • Zhu, Qing
  • Rainey, Godfrey, Jonah
  • Gao, Cuihua
  • Kasturirangan, Srinath
  • Gao, Changshou
RU2721706C2
PARTNERS OF SPECIFIC BINDING WITH NGF 2006
  • Frehnks Rut
  • Bukanan Ehndrju Grajer
  • Tom Albert Dzhordzh
  • Uehlsh Frejzer Ehving
  • Blehnd-Uord Filip Ehntoni
  • Sliman Mehtt'Ju Aleksander
  • Mehtt'Juz Karl Ehntoni
  • Khart Silija Patrisija
  • Khokinson Dzhon
RU2406728C2
HUMAN IL-13 ANTIBODY MOLECULES 2004
  • Monk Fillip Dehvid
  • Dzhermutus Lutts
  • Minter Ral'F Rejmond
  • Shorrok Silija Patrisia
RU2387667C2
MOLECULES WHICH BIND TO PSL PSEUDOMONAS, AND METHODS FOR USE THEREOF 2012
  • Didzhandomeniko Antonio
  • Uorrener Pol Dzh.
  • Stouver Charlz K.
  • Sellman Bret
  • Gillard Sandrin
  • Minter Ralf
  • Rast Stiven
  • Tomich Mladen
RU2708977C2

RU 2 360 925 C2

Authors

Fel'Dman Gejtruida M.

Dehvis Monik V.

Song Kening

Vol'Fman Nehjl M.

Grouv-Bridzhes Kristi

Fild Ehnn

Rassell Kehrolajn

Val'Ge-Arkher Fija

Dates

2009-07-10Published

2003-10-22Filed