TREATING LIVER DISEASE OR DISORDER INVOLVING USE OF ACTRII RECEPTOR ANTAGONISTS Russian patent published in 2025 - IPC A61K39/395 A61K39/00 A61K45/00 A61K45/06 A61P1/16 A61P3/04 C07K16/28 

FIELD: biotechnology.

SUBSTANCE: disclosed is the use of an activin receptor type II antibody (ActRII) or an antigen-binding fragment thereof for treating a liver disease or disorder in a subject in need thereof, where the liver disease or disorder is selected from non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH) and hepatic fibrosis, as well as the use of an activin receptor type II antibody (ActRII) or an antigen-binding fragment thereof for the manufacture of a medicament for treating a liver disease or disorder in a subject.

EFFECT: invention can be used to treat a liver disease in a subject, where the disease is selected from non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH) and hepatic fibrosis.

40 cl, 1 tbl, 10 dwg, 3 ex