BLOOD SUBSTITUTE WITH FUNCTION OF OXYGEN TRANSFER, PHARMACEUTICAL COMPOSITION (VERSIONS) Russian patent published in 2009 - IPC A61K38/42 C07K14/805 A61P7/00 

FIELD: medicine.

SUBSTANCE: group of inventions concerns medicine and pharmacology, namely to blood substitutes on the basis of polyhemoglobin. The blood substitute with function of oxygen transfer which basis is made of polymerised glutaric aldehyde haemoglobin received from blood of animals is offered, thus it represents a dry substance and contains not less than 90% of polymerised haemoglobin with molecular mass in a range 192000-320000Da, and methemoglobin content in a blood substitute makes not more than 5%. The pharmaceutical compositions containing the specified blood substitute, containing either polyvinylpyrolidone, or polyoxydin, or physiological saline, or solution of sodium chloride, potassium chloride and magnesium chloride and sodium fumarate are offered. The invention provides blood substitute creation, comparable by efficiency of oxygen transfer with erythrocytes of human blood.

EFFECT: creation of blood substitute, comparable by efficiency of oxygen transfer with erythrocytes of human blood.

10 cl, 1 ex, 1 tbl