FIELD: medicine, transfusiology.
SUBSTANCE: invention can be used to mobilize blood from the depot during acute blood loss. The use of polymerized hemoglobin in the form of a solution for infusion prepared from a lyophilisate is proposed, where the polymerized hemoglobin is hemoglobin polymerized by glutaraldehyde, obtained from cattle, with a molecular weight in the range of 192,000-320,000 Da, where the lyophilisate contains at least 90% of polymerized hemoglobin, as a means that has the properties of mobilizing blood cells from blood-depositing organs in case of acute blood loss. Polymerized hemoglobin is administered to patients in a dose of 1 to 12.6 g per day.
EFFECT: use of the invention makes it possible to restore hemodynamic and hematological parameters in the first hours after hemorrhagic shock with low doses of polymerized hemoglobin due to its properties of mobilizing blood cells from blood depositing organs.
2 cl, 8 tbl, 3 dwg, 2 ex
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